The Guerilla Render GUI has been designed around a nodal graph called the RenderGraph. This graph contains all the work done by the artists in Guerilla Render (like the shader assignements, the shader parameters, the light/trace/shadow linking, the layering) in a non-linear fashion.
One can use a RenderGraph per asset project (with the asset look development setup) and one or more RenderGraphs per shot project (with the lighting/layering/tweaking work). This workflow makes it efficient to work with a large amount of objects on a lot of shots. It is for example easy to duplicate the setup of a whole shot onto another one.